African locust bean popularly used in seasoning traditional soups has shown
promise in boosting cellular immunity in immune-compromised persons, as well as, in management of diarhhoea, diabetes, and heart attack. It could also serve as
antidote to snake bites.
THEY are used for local seasoning of soups, from bitter-leaf soup (Onugbu in Ibo) to palm fruit soup (Ofe akwu in Ibo). They come with sometimes, offensive odour, but make delicious meals. Indeed, the fermented seeds of Parkia
biglobosa and Parkia bicolor are used in all parts of Nigeria and the West Coast of Africa for seasoning traditional soups. They belong to the plant family Mimosaceae of the order Leguminisae.
P. biglobosa popularly known as the African locust bean tree is known in Yoruba as Igba, or Irugba, in Hausa as Dorowa, Nune in Tiv, and in lbo as Ogili. In Yoruba, P. bicolor is referred to as Igba odo, Dorowa, in Hausa, and in lbo as Ogili okpi.
According to a study published in Plant Biology 2010, “the seed of African locust
bean when boiled and fermented is known as dawadawa in Hausa language in Nigeria, a black strong smelling tasty seasoning, rich in lipid 29 per cent, protein 35 per cent, carbohydrate 16 per cent, good source of protein, fat and calcium for rural dweller.
“The bark is used as a mouthwash, vapour inhalant for toothache, or for ear
complaints. It is macerated in baths for leprosy and used for bronchitis, pneumonia, skin infections, sores, ulcers, washes for fever, malaria, diarrhoea, and sterility. Roots are used in a lotion for sore eyes. ”
According to The Useful Plants of West Tropical Africa by H. M. Burkill, “the
pulverised bark of P. bicolor is employed in wound healing. P. biglobosa is known to provide an ingredient that is used in treating leprosy, and for treating
hypertension. “In Gambia, the leaves and roots are used in preparing a lotion for sore eyes. A decoction of the bark of P. biglobosa is also used as a bath for fever, as a hot mouthwash to steam and relieve toothache. The pulped bark is used along with lemon for wound and ulcers. ”
But results of a recent study suggest that the aqueous extract of leaves of Parkia biglobosa stimulate the production of total lymphocytes (white blood cells) and TCD4+ (a marker of the immune system). The study published in Agriculture and Biology Journal of North America is titled “ Effects of aqueous extract of leaves of Parkia biglobosa on markers of cellular immunity in rabbit. ”
The studies of the aqueous extract of leaves of Parkia biglobosa by Ivorien researchers showed that doses of 25, 50, 75 and 100mg/kg of BW induced a significant increase both in the count of total lymphocytes count and TCD4+ count of rabbits.
The researchers concluded, “the aqueous extract of Parkia biglobosa leaves induced an increase in both the count of total lymphocytes and TCD4+ in blood. Thus, doses of 75 and 100mg/kg Body Weight (BW) mobilising more of total lymphocytes and TCD4+ in peripheral blood, and over a period of six days. To this end, the leaves of this plant contain immunostimulatory activity molecule.
“This assertion is supported by the increase in the immunosuppressive activity of
Methylprednisolone by the aqueous extract of leaves of Parkia biglobosa and the
isoprinosine. This leads us to suggest that the aqueous extract of leaves of Parkia
biglobosa would have the same mode of action than isoprinosine. Therefore, it could help strengthen the immune system of immuno-suppressed. ”
Methylprednisolone (Medrol) is in a class of drugs called steroids. It prevents the release of substances in the body that cause inflammation. Methylprednisolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.
Isoprinosine (Ip) is a prescription drug posited to have immune modulating and
Also, results of another study published in the Journal of Ethnopharmacology revealed that the aqueous methanol extracts of all the five medicinal plants, including Parkia biglobosa, investigated have pharmacological activity against diarrhoea. This may explain their use in traditional medicine for the treatment of diarrhoea. The study titled: “Evaluation of five medicinal plants used in diarrhoea
treatment in Nigeria, ” was carried out by researchers at Ahmadu Bello University,
Zaria, Kaduna State.
Also, the results of a study published in Clinical and Experimental Pharmacology and Physiology demonstrated that both aqueous and methanolic extracts of
fermented seeds of Parkia biglobosa (PB) exert a hypoglycaemic (reduces blood
glucose) effect, hence, PB has an anti- diabetic property. However, only the
aqueous extract of PB ameliorated the loss of bodyweight usually associated with diabetes. The researchers from the Department of Biochemistry, College of Medicine, University of Ibadan, wrote: “Although the aqueous extract has a favourable lipid profile, which is probably an indication of its possible anti-arteriogenic property (hypertension and ischaemic heart diseases being common complications in diabetes mellitus), the methanolic extract shows possible contraindication to ischaemic heart diseases. ”
Another research published in the Journal of Ethnopharmacology found that
procyanidin-rich fractions from Parkia biglobosa leaves caused a reduction in
Also, researchers at the Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Enugu State, have demonstrated the anti-snake venom activities of Parkia biglobosa stem bark extract. The researchers wrote in the study published in Toxicology: “We have studied
the ability of one such traditionally used plant to reduce the effects of two snake
venoms (Naja nigricollis, and Echis ocellatus)
in several experimental models. A water- methanol extract of P. biglobosa stem bark significantly protected the chick biventer cervicis (cbc) muscle preparation from N. nigricollis venom-induced inhibition of neurally evoked twitches when it was added to the bath three to five minutes before or after the venom.
“P. biglobosa extract (75, 150 and 300 microg/ml) significantly protected C2C12
murine muscle cells in culture against the cytotoxic effects of N. nigricollis and E.
ocellatus venoms. The extract protected egg embryos exposed to lethal concentrations of E. ocellatus venom for more than 12 hours and completely blocked the haemorrhagic activity of the venom at concentrations of 5 and 10 microg/1.5 microl. ”
“ P. biglobosa extract (400 mg/kg) did not protect mice injected i.p. with 5 and 2.5 mg/ kg of E. ocellatus and N. nigricollis venoms, respectively. It, however, protected 40 per cent of the mice from death caused by E. ocellatus venom after the extract and venom were pre-incubated for 30 min before injecting the mixture.”
It’s a shame that there is just not a good deal of data to choose from on the topic of staying removed from high cholesterol naturally, a large number of suggestions merely being focused on how to reduce cholesterol after it has been recognized as abnormal. A desirable method should be to attempt to make changes in your daily diet and life style right now, and undertake a practice of regular work outs together with a much healthier, cholesterol limited diet.
Avoidance is far superior to remedy and the preferred way to avoiding bad cholesterol as well as cardiovascular issues from building up, would be to check out those things we consume frequently, paying real attention to eating things that contain much lower quantities of extra fat. There’s always plenty of chat regarding careful diet, yet, choosing reduced cholesterol menus, along with ensuring some good exercise is what will surely make the real difference.
After Cholesterol has started forming within your body the material stays trapped on the inner surfaces of the arteries, preventing the easy flow of blood which is going to cause all sorts of cardiovascular related conditions and health concerns. In addition, it is extremely persistent and will not readily leave the affected arterial passageways. This makes the whole experience a tremendous cause of frustration and much worry to those folks who suffer with these related conditions.
On the large side or possibly even obese? It should be realised that it is just such people that are in all probability the ones destined to be afflicted with high-cholesterol. However, on the other hand, there could be various other causitive agents, among them poor diet regime, medicinal drugs and in-built characteristics, which are capable of having an effect on virtually anyone.
Thankfully, there are plenty of natural ways, including diets, which can aid in lowering cholesterol in the majority of men and women, because they can provide the important anti-oxidants that really do help to stop the build-up of cholesterol. It is also of great importance to understand that all cholesterol is not dangerous. LDL cholesterol is most certainly unsafe in large portions, but an alternative form of cholesterol named High-Density lipoprotein is unquestionably good for our systems and assists at fighting off the undesirable buildups of “bad” cholesterol.
There are many the types of foods that will help with this:-
LEAN MEATS – very lean beef, skin free poultry and also liver, instead of the regular red meats, alongside bacon and likewise ham, will be of great assistance in realizing reduced cholesterol levels. Also, they are very high in necessary proteins.
FRUITS AND VEGGIES – The majority of these provide copious amounts of anti-oxidants as well as other nutrients and should really be considered as a top priority to be included in large quantities, within any diet – particularly in place of processed foods.
These are most certainly extremely healthy and they both eliminate bad fats and various harmful substances which we tend to eat and thus detoxify our systems. They, in addition, contain valuable amounts of vitamins that one’s body requires in order to function correctly. An added bonus is that they never include any kind of fat. Citrus fruits which are usually packed with vitamin C ought to always be included. Cucumber, which is full of vitamin E( that’s a powerful anti oxidant), can be quite good for handling free-radicals that will often be found to be the root cause of numerous ailments.
FISH – Nearly all fish is considered most healthy, since it features virtually no unsaturated fats. In addition, the really oily fish are particularly valuable since they carry Omega-3 fats that are great for all round improvements of ones health.
WHEAT and OATMEAL – High fiber cereals are typically loaded with particularly nutritional materials and help in getting down levels of cholesterol. Numerous reports have to date been completed relating to nutrition and diet. The later ones have added the conclusion that the addition of fibrous cereal to the diet, have been successful, when coupled with any otherwise healthy and appropriate diet, in preventing many different types of cardiovascular related illnesses.
OTHER KINDS OF FIBROUS Foodstuff – These consists of rice, legumes, brewer’s yeast, wheat bran, pinto beans and many breads. They can be instrumental in enhancing the levels of “good” cholesterol found in the body.
YOGHURT – A lower fat product, it’s also most helpful in the process of the digestion of foods, mainly because it controls acids within your stomach, leaving you feeling far healthier and it is also instrumental in decreasing the creation of LDL cholesterol.
You are now equipped with good information on the means of achieving naturally lowered cholesterol with your diet. It is at this point that you should begin taking action and commence a rather healthier and far lower cholesterol, kind of life style.